My rule of thumb is no darting of a doe 30 days prior to giving birth and 4 weeks after (when the fawns began eating feed, just in case there is a catastrophy) but that's my rule, I have had to dart several days prior to fawning on an emergency basis and the fawns were born just fine. I think the dosage rate, type of drug, stress induced, temperature, etc. are extremely important if you have to dart close to fawning.