That e-coli shot Josh Newton from Red Ridge Whitetails has done me wonders. We give it to the does so the does will produce the best colostrum they can. We totally eliminated E-coli from our mule deer fawns. At a couple days old we give it to the fawns also. We also do our whitetail does but not usually the fawns. I highly recommended that product. It also takes care of lump jaw and abscess's.