Four Seasons Whitetails said:
This guy just will not admit to the fact that cwd could very well have jumped ship from sheep. If thats the case then why would he not be all over the sheep farmer to push his agenda. If the tse prion is the same in both animals then why would he not be all for the stronger testing for sheep like he is for deer? Agenda!
are you stupid or what ?
read the complete post, before putting foot in mouth.
they call that, foot-in-mouth-disease...
ban me if you must...
pens, pens, PENS ???
*** Spraker suggested an interesting explanation for the occurrence of CWD. The deer pens at the Foot Hills Campus were built some 30-40 years ago by a Dr. Bob Davis. At or abut that time, allegedly, some scrapie work was conducted at this site. When deer were introduced to the pens they occupied ground that had previously been occupied by sheep.
http://collections.europarchive.org...www.bseinquiry.gov.uk/files/mb/m11b/tab01.pdf
now, decades later ;
2012
PO-039: A comparison of scrapie and chronic wasting disease in white-tailed deer
Justin Greenlee, Jodi Smith, Eric Nicholson US Dept. Agriculture; Agricultural Research Service, National Animal Disease Center; Ames, IA USA
snip...
The results of this study suggest that there are many similarities in the manifestation of CWD and scrapie in WTD after IC inoculation including early and widespread presence of PrPSc in lymphoid tissues, clinical signs of depression and weight loss progressing to wasting, and an incubation time of 21-23 months. Moreover, western blots (WB) done on brain material from the obex region have a molecular profile similar to CWD and distinct from tissues of the cerebrum or the scrapie inoculum. However, results of microscopic and IHC examination indicate that there are differences between the lesions expected in CWD and those that occur in deer with scrapie: amyloid plaques were not noted in any sections of brain examined from these deer and the pattern of immunoreactivity by IHC was diffuse rather than plaque-like. After a natural route of exposure, 100% of WTD were susceptible to scrapie. Deer developed clinical signs of wasting and mental depression and were necropsied from 28 to 33 months PI. Tissues from these deer were positive for PrPSc by IHC and WB. Similar to IC inoculated deer, samples from these deer exhibited two different molecular profiles: samples from obex resembled CWD whereas those from cerebrum were similar to the original scrapie inoculum. On further examination by WB using a panel of antibodies, the tissues from deer with scrapie exhibit properties differing from tissues either from sheep with scrapie or WTD with CWD. Samples from WTD with CWD or sheep with scrapie are strongly immunoreactive when probed with mAb P4, however, samples from WTD with scrapie are only weakly immunoreactive. In contrast, when probed with mAb’s 6H4 or SAF 84, samples from sheep with scrapie and WTD with CWD are weakly immunoreactive and samples from WTD with scrapie are strongly positive. This work demonstrates that WTD are highly susceptible to sheep scrapie, but on first passage, scrapie in WTD is differentiable from CWD.
http://www.landesbioscience.com/journals/prion/03-Prion6-2-Transmission-and-strains.pdf
2011
*** After a natural route of exposure, 100% of white-tailed deer were susceptible to scrapie.
http://www.usaha.org/Portals/6/Reports/2011/report-cwal-2011.pdf
Scrapie in Deer: Comparisons and Contrasts to Chronic Wasting Disease (CWD)
Justin J. Greenlee of the Virus and Prion Diseases Research Unit, National Animal Disease Center, ARS, USDA, Ames, IA
snip...
This highlights the facts that 1) prior to the onset of clinical signs PrPSc is widely distributed in the CNS and lymphoid tissues and 2) currently used diagnostic methods are sufficient to detect PrPSc prior to the onset of clinical signs. The results of this study suggest that there are many similarities in the manifestation of CWD and scrapie in white-tailed deer after IC inoculation including early and widespread presence of PrPSc in lymphoid tissues, clinical signs of depression and weight loss progressing to wasting, and an incubation time of 21-23 months. Moreover, western blots (WB) done on brain material from the obex region have a molecular profile consistent with CWD and distinct from tissues of the cerebrum or the scrapie inoculum. However, results of microscopic and IHC examination indicate that there are differences between the lesions expected in CWD and those that occur in deer with scrapie: amyloid plaques were not noted in any sections of brain examined from these deer and the pattern of immunoreactivity by IHC was diffuse rather than plaque-like. After a natural route of exposure, 100% of white-tailed deer were susceptible to scrapie. Deer developed clinical signs of wasting and mental depression and were necropsied from 28 to 33 months PI. Tissues from these deer were positive for scrapie by IHC and WB. Tissues with PrPSc immunoreactivity included brain, tonsil, retropharyngeal and mesenteric lymph nodes, hemal node, Peyer’s patches, and spleen. While two WB patterns have been detected in brain regions of deer inoculated by the natural route, unlike the IC inoculated deer, the pattern similar to the scrapie inoculum predominates.
http://www.usaha.org/Portals/6/Reports/2011/report-cwal-2011.pdf
2011 Annual Report
Research Project: TRANSMISSION, DIFFERENTIATION, AND PATHOBIOLOGY OF TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES Location: Virus and Prion Research Unit
2011 Annual Report
In Objective 1, Assess cross-species transmissibility of transmissible spongiform encephalopathies (TSEs) in livestock and wildlife, numerous experiments assessing the susceptibility of various TSEs in different host species were conducted. Most notable is deer inoculated with scrapie, which exhibits similarities to chronic wasting disease (CWD) in deer suggestive of sheep scrapie as an origin of CWD.
snip...
4.Accomplishments 1. Deer inoculated with domestic isolates of sheep scrapie. Scrapie-affected deer exhibit 2 different patterns of disease associated prion protein. In some regions of the brain the pattern is much like that observed for scrapie, while in others it is more like chronic wasting disease (CWD), the transmissible spongiform encephalopathy typically associated with deer. This work conducted by ARS scientists at the National Animal Disease Center, Ames, IA suggests that an interspecies transmission of sheep scrapie to deer may have been the origin of CWD. This is important for husbandry practices with both captive deer, elk and sheep for farmers and ranchers attempting to keep their herds and flocks free of CWD and scrapie.
http://ars.usda.gov/research/projects/projects.htm?ACCN_NO=411467&showpars=true&fy=2011
White-tailed Deer are Susceptible to Scrapie by Natural Route of Infection
Jodi D. Smith, Justin J. Greenlee, and Robert A. Kunkle; Virus and Prion Research Unit, National Animal Disease Center, USDA-ARS
snip...
This work demonstrates for the first time that white-tailed deer are susceptible to sheep scrapie by potential natural routes of inoculation. In-depth analysis of tissues will be done to determine similarities between scrapie in deer after intracranial and oral/intranasal inoculation and chronic wasting disease resulting from similar routes of inoculation.
see full text ;
http://www.usaha.org/Portals/6/Reports/2010/report-cwal-2010.pdf
SEE MORE USAHA REPORTS HERE, 2012 NOT PUBLISHED YET...TSS
http://www.usaha.org/Portals/6/Proceedings/USAHAProceedings-2010-114th.pdf
http://www.usaha.org/Portals/6/Proceedings/2009_USAHA_Proceedings.pdf
http://portals5.gomembers.com/portals/6/proceedings/2008_usaha_proceedings.pdf
Thursday, June 20, 2013
atypical, BSE, CWD, Scrapie, Captive Farmed shooting pens (livestock), Wild Cervids, Rectal Mucosa Biopsy 2012 USAHA Proceedings, and CJD TSE prion Update
http://transmissiblespongiformencep.../atypical-bse-cwd-scrapie-captive-farmed.html
*** The potential impact of prion diseases on human health was greatly magnified by the recognition that interspecies transfer of BSE to humans by beef ingestion resulted in vCJD. While changes in animal feed constituents and slaughter practices appear to have curtailed vCJD, there is concern that CWD of free-ranging deer and elk in the U.S. might also cross the species barrier. Thus, consuming venison could be a source of human prion disease. Whether BSE and CWD represent interspecies scrapie transfer or are newly arisen prion diseases is unknown. Therefore, the possibility of transmission of prion disease through other food animals cannot be ruled out. There is evidence that vCJD can be transmitted through blood transfusion. There is likely a pool of unknown size of asymptomatic individuals infected with vCJD, and there may be asymptomatic individuals infected with the CWD equivalent. These circumstances represent a potential threat to blood, blood products, and plasma supplies.
http://cdmrp.army.mil/prevfunded/nprp/NPRP_Summit_Final_Report.pdf
snip...
greetings, my feelings about shooting pens are my feelings, they are not law. the science I try to bring to the public domain, it speaks for itself, and has for a great many years, via a bunch of wonderful dedicated scientist around the world. rhonda brings up a very good point above, on the difference in scrapie and CWD regulations (for game farmers regulations). let me tell you this. the usda inc is doing it’s best to eliminate all TSE prion regulations through the OIE. if you shooting pen owners could get hooked up with the OIE as the USDA inc is, it would be all clear sailing for you then, because that is the goal of the OIE as well.
I thought this might be important for you game farmers, you might find it interesting, because I do agree that you are being dealt with differently in regards to cwd regulations and scrapie, but how I see the problem and risk factors from the TSE prion disease due to this disregard of science, and how the shooting pen owners would look at it, is different. the shooting pens are, if I understand it correctly, are upset because they don’t have the same regulations as scrapie, and ramifications financially there from, and the shooting pens want their regulations weakened to the scrapie regulations level. ...give it time, you’ll be good to go, because the usda inc. et al threw sound science out the window a long time ago. ...cheers!
====================================
XXXXXX--IMPORTANT TSE HISTORY--XXXXXX
====================================
DECLARATION OF EXTRAORDINARY EMERGENCY BECAUSE OF AN ATYPICAL T.S.E. (PRION DISEASE) OF FOREIGN ORIGIN IN THE UNITED STATES [Docket No. 00-072-1]
6. WHAT happened to the test results and MOUSE BIO-ASSAYS of those
imported sheep from Belgium that were confiscated and slaughtered from the
Faillace's, what sort of TSE did these animals have ? Imported
Belgium/Netherlands Sheep Test Results Background Factsheet Veterinary
Services April 2002 APHIS ...snip...
7. WHY is it that the Farm of the Mad Sheep of Mad River Valley were
quarantined for 5 years, but none of these farms from Texas and Alabama
with Atypical TSE in the Bovine, they have not been quarantined for 5
years, why not, with the real risk of BSE to sheep, whom is to say this
was not BSE ? (see later results via FOIA below...TSS)...snip
http://www.fsis.usda.gov/OPPDE/Comments/2006-0011/2006-0011-1.pdf
Tuesday, November 13, 2007
DECLARATION OF EXTRAORDINARY EMERGENCY BECAUSE OF AN ATYPICAL T.S.E. (PRION DISEASE) OF FOREIGN ORIGIN IN THE UNITED STATES [Docket No. 00-072-1]
To:
[email protected]
CC:
[email protected];
[email protected];
Re: FOIA APPEAL 07-566 DECLARATION OF EXTRAORDINARY EMERGENCY BECAUSE OF AN ATYPICAL T.S.E. (PRION DISEASE) OF FOREIGN ORIGIN IN THE UNITED STATES [Docket No. 00-072-1]
http://foiamadsheepmadrivervalley.blogspot.com/2007/11/declaration-of-extraordinary-emergency.html
EXACTLY WHAT are these people capable of doing ???
JUST HOW FAR will they go ???
Mad Sheep The True Story Behind the USDA‚ War on a Family Farm Linda Faillace
The page-turning account of a government cover-up, corporate greed, and a courageous family‚ fight to save their farm.
http://www.chelseagreen.com/bookstore/item/mad_sheep/
http://www.rutlandherald.com/apps/pbcs.dll/article?AID=/20060903/NEWS/609030376/
FOIA OF DECLARATION OF EXTRAORDINARY EMERGENCY BECAUSE OF AN ATYPICAL T.S.E. (PRION DISEASE) OF FOREIGN ORIGIN IN THE UNITED STATES [Docket No. 00-072-1]
http://foiamadsheepmadrivervalley.blogspot.com/
snip...
see, and please read, the full test, before shooting the messenger ;
or not, lock and load, and fire away ;
Wednesday, August 21, 2013
IOWA DNR EMERGENCY CONSENT ORDER IN THE MATTER OF TOM & LINDA BRAKKE D/B/A PINE RIDGE HUNTING LODGE UPDATE AUGUST 21, 2013
http://chronic-wasting-disease.blogspot.com/2013/08/iowa-dnr-emergency-consent-order-in.html
fire away...
kind regards,
terry