I am no expert, but I can relay this one story. I have a relative that is a vet. He is not located too close to us, so he's not our regular vet. He gives me a bottle of Tolazoline one day and says I can have it if I want to try it. A client of his said it didn't work (on deer)- they just wouldn't wake up. The guy apparently wasn't a newby with deer, either. I figure I will find out quickly if the guy is right or not. We have used that bottle on at least a dozen sedations since with no problems. I have no idea what the deal was.
I guess the moral of the story is that tranquilizations (at least with Xylazine/Telazol reversed with Tolazoline) are situations that don't always look exactly the same from one time to the next. Heck I thought I killed a buck last fall with a normal dose of 6:1 (100mg X) cocktail (respiration stopped a couple times- compressions to the chest seemed to kick him back in gear), yet he was good to go in normal time once reversed. This year we had a similar size buck that needed topped off after a healthy dose of the same strength cocktail (almost twice the total dosage) just to get him sleeping. Neither were especially tame or wild.
I am basically decided that we are going to order a couple kits of BAM if our vet doesn't wring a zillion dollars out of us to write the scrip. I like the predictability that I hear about regarding BAM. Also, the price of telazol is disgusting in this area.